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Insulin Resistance Negatively Influences the Muscle-Dependent IGF-1-Bone Mass Relationship in Premenarcheal Girls

CONTEXT: IGF-1 promotes bone growth directly and indirectly through its effects on skeletal muscle. Insulin and IGF-1 share a common cellular signaling process; thus, insulin resistance may influence the IGF-1-muscle-bone relationship. OBJECTIVE: We sought to determine the effect of insulin resistan...

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Détails bibliographiques
Publié dans:J Clin Endocrinol Metab
Auteurs principaux: Kindler, J. M., Pollock, N. K., Laing, E. M., Jenkins, N. T., Oshri, A., Isales, C., Hamrick, M., Lewis, R. D.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701844/
https://ncbi.nlm.nih.gov/pubmed/26574958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-3451
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