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Redirection of the Reaction Specificity of a Thermophilic Acetolactate Synthase toward Acetaldehyde Formation

Acetolactate synthase and pyruvate decarboxylase are thiamine pyrophosphate-dependent enzymes that convert pyruvate into acetolactate and acetaldehyde, respectively. Although the former are encoded in the genomes of many thermophiles and hyperthermophiles, the latter has been found only in mesophili...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Cheng, Maria, Yoshiyasu, Hayato, Okano, Kenji, Ohtake, Hisao, Honda, Kohsuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701669/
https://ncbi.nlm.nih.gov/pubmed/26731734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146146
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