Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells

Sphingolipids make up a family of molecules associated with an array of biological functions, including cell death and migration. Sphingolipids are often altered in cancer, though how these alterations lead to tumor formation and progression is largely unknown. Here, we analyzed non–small-cell lung...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Suzuki, Motoshi, Cao, Ke, Kato, Seiichi, Komizu, Yuji, Mizutani, Naoki, Tanaka, Kouji, Arima, Chinatsu, Tai, Mei Chee, Yanagisawa, Kiyoshi, Togawa, Norie, Shiraishi, Takahiro, Usami, Noriyasu, Taniguchi, Tetsuo, Fukui, Takayuki, Yokoi, Kohei, Wakahara, Keiko, Hasegawa, Yoshinori, Mizutani, Yukiko, Igarashi, Yasuyuki, Inokuchi, Jin-ichi, Iwaki, Soichiro, Fujii, Satoshi, Satou, Akira, Matsumoto, Yoko, Ueoka, Ryuichi, Tamiya-Koizumi, Keiko, Murate, Takashi, Nakamura, Mitsuhiro, Kyogashima, Mamoru, Takahashi, Takashi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701566/
https://ncbi.nlm.nih.gov/pubmed/26650179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79775
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