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Selection bias: maintaining less-differentiated T cells for adoptive immunotherapy
The clinical application of T cell immunotherapy depends on ex vivo modification and expansion of T cells for adoptive transfer. In preclinical models, the use of a purified, naive T cell subset enhances persistence and antitumor immunity; however, the majority of clinical studies rely on modificati...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701555/ https://ncbi.nlm.nih.gov/pubmed/26657855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85631 |
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