The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice

BACKGROUND & AIMS: In recent years, nonalcoholic steatohepatitis (NASH) has become a considerable healthcare burden worldwide. Pathogenesis of NASH is associated with type 2 diabetes mellitus (T2DM) and insulin resistance. However, a specific drug to treat NASH is lacking. We investigated the ef...

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Veröffentlicht in:PLoS One
Hauptverfasser: Honda, Yasushi, Imajo, Kento, Kato, Takayuki, Kessoku, Takaomi, Ogawa, Yuji, Tomeno, Wataru, Kato, Shingo, Mawatari, Hironori, Fujita, Koji, Yoneda, Masato, Saito, Satoru, Nakajima, Atsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701474/
https://ncbi.nlm.nih.gov/pubmed/26731267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146337
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