IL-10- and TGFβ-mediated Th9 Responses in a Human Helminth Infection

BACKGROUND: Th9 cells are a subset of CD4(+) T cells that express the protoypical cytokine, IL-9. Th9 cells are known to effect protective immunity in animal models of intestinal helminth infections. However, the role of Th9 cells in human intestinal helminth infections has never been examined. METH...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Anuradha, Rajamanickam, Munisankar, Saravanan, Bhootra, Yukthi, Jagannathan, Jeeva, Dolla, Chandrakumar, Kumaran, Paul, Nutman, Thomas B., Babu, Subash
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701466/
https://ncbi.nlm.nih.gov/pubmed/26730582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004317
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