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Dimerization and DNA binding alter phosphorylation of Fos and Jun.

Fos and Jun form dimeric complexes that bind to activator protein 1 (AP-1) DNA sequences and regulate gene expression. The levels of expression and activities of these proteins are regulated by a variety of extracellular stimuli. They are thought to function in nuclear signal transduction processes...

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Autors principals: Abate, C, Baker, S J, Lees-Miller, S P, Anderson, C W, Marshak, D R, Curran, T
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC47013/
https://ncbi.nlm.nih.gov/pubmed/8341696
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