Dimethyl fumarate treatment alters circulating T helper cell subsets in multiple sclerosis

OBJECTIVE: To evaluate the effect of dimethyl fumarate (DMF; Tecfidera, Biogen, Weston, MA) on CD4(+) and CD8(+) T cell subsets in patients with multiple sclerosis (MS). METHODS: Peripheral lymphocyte subsets, including CD4(+) and CD8(+) memory cells and T helper (T(H)) cells T(H)1, T(H)2, T(H)17, a...

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Bibliographic Details
Published in:Neurol Neuroimmunol Neuroinflamm
Main Authors: Gross, Catharina C., Schulte-Mecklenbeck, Andreas, Klinsing, Svenja, Posevitz-Fejfár, Anita, Wiendl, Heinz, Klotz, Luisa
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701136/
https://ncbi.nlm.nih.gov/pubmed/26767188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000183
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