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Expression Differentiation Is Constrained to Low-Expression Proteins over Ecological Timescales

Protein expression level is one of the strongest predictors of protein sequence evolutionary rate, with high-expression protein sequences evolving at slower rates than low-expression protein sequences largely because of constraints on protein folding and function. Expression evolutionary rates also...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Margres, Mark J., Wray, Kenneth P., Seavy, Margaret, McGivern, James J., Herrera, Nathanael D., Rokyta, Darin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701091/
https://ncbi.nlm.nih.gov/pubmed/26546003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.180547
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