Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation

Neural tube defects including spina bifida are common and severe congenital disorders. In mice, mutations in more than 200 genes can result in neural tube defects. We hypothesized that this large gene set might include genes whose homologs contribute to morphogenesis in diverse animals. To test this...

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Publicado en:Genetics
Main Authors: Sullivan-Brown, Jessica L., Tandon, Panna, Bird, Kim E., Dickinson, Daniel J., Tintori, Sophia C., Heppert, Jennifer K., Meserve, Joy H., Trogden, Kathryn P., Orlowski, Sara K., Conlon, Frank L., Goldstein, Bob
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2016
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Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701080/
https://ncbi.nlm.nih.gov/pubmed/26434722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.183137
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