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MicroRNA-15b/16 attenuates vascular neointima formation by promoting the contractile phenotype of vascular smooth muscle through targeting YAP

OBJECTIVE: To investigate the functional role of the miR-15b/16 in vascular smooth muscle phenotypic modulation. APPROACH AND RESULTS: We found that miR-15b/16 is the one of most abundant microRNAs expressed in contractile vascular smooth muscle cells (VSMCs). However, when contractile VSMCs convert...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Xu, Fei, Ahmed, Abu Shufian Ishtiaq, Kang, Xiuhua, Hu, Guoqing, Liu, Fang, Zhang, Wei, Zhou, Jiliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701035/
https://ncbi.nlm.nih.gov/pubmed/26293467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305748
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