Association between Regimen Composition and Treatment Response in Patients with Multidrug-Resistant Tuberculosis: A Prospective Cohort Study

BACKGROUND: For treating multidrug-resistant tuberculosis (MDR TB), the World Health Organization (WHO) recommends a regimen of at least four second-line drugs that are likely to be effective as well as pyrazinamide. WHO guidelines indicate only marginal benefit for regimens based directly on drug s...

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Veröffentlicht in:PLoS Med
Hauptverfasser: Yuen, Courtney M., Kurbatova, Ekaterina V., Tupasi, Thelma, Caoili, Janice Campos, Van Der Walt, Martie, Kvasnovsky, Charlotte, Yagui, Martin, Bayona, Jaime, Contreras, Carmen, Leimane, Vaira, Ershova, Julia, Via, Laura E., Kim, HeeJin, Akksilp, Somsak, Kazennyy, Boris Y., Volchenkov, Grigory V., Jou, Ruwen, Kliiman, Kai, Demikhova, Olga V., Vasilyeva, Irina A., Dalton, Tracy, Cegielski, J. Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700973/
https://ncbi.nlm.nih.gov/pubmed/26714320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001932
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