The effects of transfection reagent polyethyleneimine (PEI) and non-targeting control siRNAs on global gene expression in human aortic smooth muscle cells

BACKGROUND: RNA interference (RNAi) is a powerful platform utilized to target transcription of specific genes and downregulate the protein product. To achieve effective silencing, RNAi is usually applied to cells or tissue with a transfection reagent to enhance entry into cells. A commonly used cont...

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Publicado en:BMC Genomics
Autores principales: Raof, Nurazhani A., Rajamani, Deepa, Chu, Hsun-Chieh, Gurav, Aniket, Johnson, Joel M., LoGerfo, Frank W., Pradhan-Nabzdyk, Leena, Bhasin, Manoj
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700750/
https://ncbi.nlm.nih.gov/pubmed/26728506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2267-9
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