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The structure of a prophenoloxidase (PPO) from Anopheles gambiae provides new insights into the mechanism of PPO activation

BACKGROUND: Phenoloxidase (PO)-catalyzed melanization is a universal defense mechanism of insects against pathogenic and parasitic infections. In mosquitos such as Anopheles gambiae, melanotic encapsulation is a resistance mechanism against certain parasites that cause malaria and filariasis. PO is...

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Veröffentlicht in:BMC Biol
Hauptverfasser: Hu, Yingxia, Wang, Yang, Deng, Junpeng, Jiang, Haobo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700666/
https://ncbi.nlm.nih.gov/pubmed/26732497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0225-2
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