TGF-β1/FGF-2 signaling mediates the 15-HETE-induced differentiation of adventitial fibroblasts into myofibroblasts

BACKGROUND: Pulmonary adventitial fibroblasts (PAFs) are activated under stress stimuli leading to their differentiation into myofibroblasts, which is involved in vessel remodeling. 15-HETE is known as an important factor in vessel remodeling under hypoxia; however, the role of 15-HETE in PAF phenot...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Zhang, Li, Chen, Yan, Li, Guixia, Chen, Minggang, Huang, Wei, Liu, Yanrui, Li, Yumei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700586/
https://ncbi.nlm.nih.gov/pubmed/26729053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-015-0174-3
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