LmABCB3, an atypical mitochondrial ABC transporter essential for Leishmania major virulence, acts in heme and cytosolic iron/sulfur clusters biogenesis

BACKGROUND: Mitochondria play essential biological functions including the synthesis and trafficking of porphyrins and iron/sulfur clusters (ISC), processes that in mammals involve the mitochondrial ATP-Binding Cassette (ABC) transporters ABCB6 and ABCB7, respectively. The mitochondrion of pathogeni...

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Bibliographic Details
Published in:Parasit Vectors
Main Authors: Martínez-García, Marta, Campos-Salinas, Jenny, Cabello-Donayre, María, Pineda-Molina, Estela, Gálvez, Francisco J., Orrego, Lina M., Sánchez-Cañete, María P., Malagarie-Cazenave, Sophie, Koeller, David M., Pérez-Victoria, José M.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700571/
https://ncbi.nlm.nih.gov/pubmed/26728034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-015-1284-5
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