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Chronic effects of ethanol and/or darunavir/ritonavir on U937 monocytic cells: Regulation of cytochrome P450 and antioxidant enzymes, oxidative stress, and cytotoxicity

BACKGROUND: Our recent study has shown that acute treatment with ethanol increases oxidative stress and cytotoxicity through cytochrome P450 2E1 (CYP2E1)-mediated pathway in U937 monocytic cells. U937 cells are derived from blood monocytes and are considered as the model system for HIV-related study...

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Podrobná bibliografie
Vydáno v:Alcohol Clin Exp Res
Hlavní autoři: Rao, P.S.S., Kumar, Santosh
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700550/
https://ncbi.nlm.nih.gov/pubmed/26727525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12938
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