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Serum Autotaxin/ENPP2 Correlates with Insulin Resistance in Older Humans with Obesity

OBJECTIVE: Autotaxin (ATX) is an adipocyte-derived lysophospholipase D that generates the lipid signaling molecule lysophosphatidic acid (LPA). The ATX/LPA pathway in adipose tissue has recently been implicated in obesity and insulin resistance in animal models, but the role of circulating ATX in hu...

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Detalhes bibliográficos
Publicado no:Obesity (Silver Spring)
Principais autores: Reeves, Valerie L., Trybula, Joy S., Wills, Rachel C., Goodpaster, Bret H., Dubé, John J., Kienesberger, Petra C., Kershaw, Erin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700540/
https://ncbi.nlm.nih.gov/pubmed/26727116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21232
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