Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells

Metformin can induce breast cancer (BC) cell apoptosis and reduce BC local and metastatic growth in preclinical models. Since Metformin is frequently used along with Aspirin or beta-blockers, we investigated the effect of Metformin, Aspirin and the beta-blocker Atenolol in several BC models. In vitr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Talarico, Giovanna, Orecchioni, Stefania, Dallaglio, Katiuscia, Reggiani, Francesca, Mancuso, Patrizia, Calleri, Angelica, Gregato, Giuliana, Labanca, Valentina, Rossi, Teresa, Noonan, Douglas M., Albini, Adriana, Bertolini, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700497/
https://ncbi.nlm.nih.gov/pubmed/26728433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18673
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