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Bacterial Proliferation: Keep Dividing and Don't Mind the Gap

DNA Damage Tolerance (DDT) mechanisms help dealing with unrepaired DNA lesions that block replication and challenge genome integrity. Previous in vitro studies showed that the bacterial replicase is able to re-prime downstream of a DNA lesion, leaving behind a single-stranded DNA gap. The question r...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Laureti, Luisa, Demol, Julien, Fuchs, Robert P., Pagès, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699847/
https://ncbi.nlm.nih.gov/pubmed/26713761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005757
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