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Antitumor activity of Type I and Type III interferons in BNL hepatoma model

Hepatocellular carcinoma (HCC) occurs most commonly secondary to cirrhosis due to chronic hepatitis C or B virus (HCV/HBV) infections. Type I interferon (IFN-α) treatment of chronic HCV/HBV infections reduces the incidence of HCC in cirrhotic patients. However, IFN-α toxicity limits its tolerability...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Abushahba, Walid, Balan, Murugabaskar, Castaneda, Ismael, Yuan, Yao, Reuhl, Kenneth, Raveche, Elizabeth, de la Torre, Andrew, Lasfar, Ahmed, Kotenko, Sergei V.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699672/
https://ncbi.nlm.nih.gov/pubmed/20217081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0831-3
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