Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry

BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease affecting mostly children but also adults and characterized by hyperinflammatory features. A subset of patients, referred to as having familial hemophagocytic lymphohistiocytosis (FHL), have various underlying ge...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Cetica, Valentina, Sieni, Elena, Pende, Daniela, Danesino, Cesare, De Fusco, Carmen, Locatelli, Franco, Micalizzi, Concetta, Putti, Maria Caterina, Biondi, Andrea, Fagioli, Franca, Moretta, Lorenzo, Griffiths, Gillian M., Luzzatto, Lucio, Aricò, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: Mosby 2016
Assuntos:
Immune Deficiencies, Infection, and Systemic Immune Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699615/
https://ncbi.nlm.nih.gov/pubmed/26342526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.06.048
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