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Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging

BACKGROUND: Caloric restriction (CR) can increase longevity in rodents and improve memory function in humans. α-Lipoic acid (LA) has been shown to improve memory function in rats, but not longevity. While studies have looked at survival in rodents after switching from one diet to another, the underl...

詳細記述

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書誌詳細
出版年:Genome Biol
主要な著者: Wood, Shona H., van Dam, Sipko, Craig, Thomas, Tacutu, Robi, O’Toole, Amy, Merry, Brian J., de Magalhães, João Pedro
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699360/
https://ncbi.nlm.nih.gov/pubmed/26694192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0847-2
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