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ALK inhibitors in non-small cell lung cancer: the latest evidence and developments

The treatment of patients with advanced non-small cell lung cancer (NSCLC) harbouring chromosomal rearrangements of ALK (anaplastic lymphoma kinase) was revolutionized by crizotinib, a small molecule inhibitor of ALK, ROS1 and MET. Unfortunately, the disease progressed within the first 12 months in...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Sullivan, Ivana, Planchard, David
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699265/
https://ncbi.nlm.nih.gov/pubmed/26753004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834015617355
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