Hydrogel-Forming Microneedle Arrays Allow Detection of Drugs and Glucose In Vivo: Potential for Use in Diagnosis and Therapeutic Drug Monitoring

We describe, for the first time the use of hydrogel-forming microneedle (MN) arrays for minimally-invasive extraction and quantification of drug substances and glucose from skin in vitro and in vivo. MN prepared from aqueous blends of hydrolysed poly(methyl-vinylether-co-maleic anhydride) (11.1% w/w...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Caffarel-Salvador, Ester, Brady, Aaron J., Eltayib, Eyman, Meng, Teng, Alonso-Vicente, Ana, Gonzalez-Vazquez, Patricia, Torrisi, Barbara M., Vicente-Perez, Eva Maria, Mooney, Karen, Jones, David S., Bell, Steven E. J., McCoy, Colin P., McCarthy, Helen O., McElnay, James C., Donnelly, Ryan F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699208/
https://ncbi.nlm.nih.gov/pubmed/26717198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145644
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires