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Improved Chromatographic Separation of Sitagliptin Phosphate and Metformin Hydrochloride

New UPLC method was developed for determination of sitagliptin and metformin using Symmetry C(18) column (100 mm × 2.1 mm, 2.2 μm) and isocratic elution (methanol 20%), pH (3.5) as a mobile phase. The ultraviolet detector was operated at 220 nm and the column temperature was 50°C. Linearity paramete...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biomed Sci
1. Verfasser: Hendy, Moataz S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Master Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699135/
https://ncbi.nlm.nih.gov/pubmed/26759536
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