Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice

In diabetic nephropathy (DN) proinflammatory chemokines and leukocyte infiltration correlate with tubulointerstitial injury and declining renal function. The atypical chemokine receptor ACKR2 is a chemokine scavenger receptor which binds and sequesters many inflammatory CC chemokines but does not tr...

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Veröffentlicht in:J Diabetes Res
Hauptverfasser: Zheng, Shirong, Coventry, Susan, Cai, Lu, Powell, David W., Jala, Venkatakrishna R., Haribabu, Bodduluri, Epstein, Paul N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699014/
https://ncbi.nlm.nih.gov/pubmed/26798651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5362506
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