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A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications

Diabetic nephropathy (DN), a microvascular complication occurring in approximately 20–40% of patients with type 2 diabetes mellitus (T2DM), is characterized by the progressive impairment of glomerular filtration and the development of Kimmelstiel-Wilson lesions leading to end-stage renal failure (ES...

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Bibliografske podrobnosti
izdano v:J Diabetes Res
Main Authors: Conserva, Francesca, Gesualdo, Loreto, Papale, Massimo
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698547/
https://ncbi.nlm.nih.gov/pubmed/26798653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7934504
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