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Loss of functional connectivity is greater outside the default mode network in non-familial early-onset Alzheimer’s disease variants

The common and specific involvement of brain networks in clinical variants of Alzheimer’s disease (AD) is not well understood. We performed task-free (“resting-state”) functional imaging in 60 non-familial AD patients, including 20 early-onset AD (EOAD, age at onset <65 years, amnestic/dysexecuti...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Lehmann, Manja, Madison, Cindee, Ghosh, Pia M., Miller, Zachary A., Greicius, Michael D., Kramer, Joel H., Coppola, Giovanni, Miller, Bruce L., Jagust, William J., Gorno-Tempini, Maria L., Seeley, William W., Rabinovici, Gil D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698410/
https://ncbi.nlm.nih.gov/pubmed/26242705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.06.029
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