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Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca(2+), Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy

Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further connections via laminin to other extracellular matrix proteins. Initially considered a structural complex that protec...

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Detalhes bibliográficos
Publicado no:Physiol Rev
Main Authors: Allen, David G., Whitehead, Nicholas P., Froehner, Stanley C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698395/
https://ncbi.nlm.nih.gov/pubmed/26676145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00007.2015
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