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Aquaporin-1 shifts the critical transmural pressure to compress the aortic intima and change transmural flow: theory and implications

Transmural-pressure (ΔP)-driven plasma advection carries macromolecules into the vessel wall, the earliest prelesion atherosclerotic event. The wall's hydraulic conductivity, L(P), the water flux-to-ΔP ratio, is high at low pressures, rapidly decreases, and remains flat to high pressures (Baldw...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Joshi, Shripad, Jan, Kung-Ming, Rumschitzki, David S.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698378/
https://ncbi.nlm.nih.gov/pubmed/26342066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00316.2015
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