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Insights into open/closed conformations of the catalytically active human guanylate kinase as investigated by small-angle X-ray scattering

ABSTRACT: Bio-catalysis is the outcome of a subtle interplay between internal motions in enzymes and chemical kinetics. Small-angle X-ray scattering (SAXS) investigation of an enzyme’s internal motions during catalysis offers an integral view of the protein’s structural plasticity, dynamics, and fun...

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Vydáno v:Eur Biophys J
Hlavní autoři: Jain, Rohit, Khan, Nazimuddin, Menzel, Andreas, Rajkovic, Ivan, Konrad, Manfred, Techert, Simone
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698301/
https://ncbi.nlm.nih.gov/pubmed/26446352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-015-1079-9
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