Variation in CYP2A6 and tobacco dependence throughout adolescence and in young adult smokers

BACKGROUND: Smoking is influenced by genetic factors including variation in CYP2A6 and CYP2B6, which encode nicotine-metabolizing enzymes. In early adolescence, CYP2A6 slow nicotine metabolism was associated with higher dependence acquisition, but reduced cigarette consumption. Here we extend this w...

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Vydáno v:Drug Alcohol Depend
Hlavní autoři: Chenoweth, Meghan J., Sylvestre, Marie-Pierre, Contreras, Gisele, Novalen, Maria, O’Loughlin, Jennifer, Tyndale, Rachel F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698159/
https://ncbi.nlm.nih.gov/pubmed/26644138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2015.11.017
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