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Type I interferon transcriptional signature in neutrophils and high frequency of low-density granulocytes are associated with tissue damage in malaria

Neutrophils are the most abundant leukocyte population in the bloodstream, the primary compartment of Plasmodium sp. infection. Yet, the role of these polymorphonuclear cells in mediating either resistance or pathogenesis of malaria is poorly understood. We report that circulating neutrophils from m...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Rocha, Bruno Coelho, Marques, Pedro Elias, Leoratti, Fabiana Maria de Souza, Junqueira, Caroline, Pereira, Dhelio Batista, Antonelli, Lis Ribeiro do Valle, Menezes, Gustavo Batista, Golenbock, Douglas Taylor, Gazzinelli, Ricardo Tostes
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698035/
https://ncbi.nlm.nih.gov/pubmed/26711347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.055
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