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The Anti-Adipogenic Potential of COUP-TFII Is Mediated by Downregulation of the Notch Target Gene Hey1

BACKGROUND: Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) belongs to the steroid/thyroid hormone receptor superfamily and may contribute to the pathogenesis of obesity. It has not conclusively been established, however, whether its role is pro- or anti-adipogenic. METHODS A...

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Udgivet i:PLoS One
Main Authors: Scroyen, Ilse, Bauters, Dries, Vranckx, Christine, Lijnen, H. Roger
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697848/
https://ncbi.nlm.nih.gov/pubmed/26719988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145608
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