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Fluorescent microscopy as a tool to elucidate dysfunction and mislocalization of Golgi glycosyltransferases in COG complex depleted mammalian cells

Staining of molecules such as proteins and glycoconjugates allows for an analysis of their localization within the cell and provides insight into their functional status. Glycosyltransferases, a class of enzymes which are responsible for glycosylating host proteins, are mostly localized to the Golgi...

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Bibliografische gegevens
Gepubliceerd in:Methods Mol Biol
Hoofdauteurs: Willett, Rose A, Pokrovskaya, Irina D, Lupashin, Vladimir V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697733/
https://ncbi.nlm.nih.gov/pubmed/23765654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-465-4_6
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