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Histone methyltransferases: novel targets for tumor and developmental defects

Histone lysine methylation plays a critical role in epigenetic regulation of eukaryotes. To date, studies have shown that lysine residues of K4, K9, K27, K36 and K79 in histone H3 and K20 in histone H4 can be modified by histone methyltransferases (HMTs). Such histone methylation can specifically ac...

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Publicat a:Am J Transl Res
Autors principals: Yi, Xin, Jiang, Xue-Jun, Li, Xiao-Yan, Jiang, Ding-Sheng
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697697/
https://ncbi.nlm.nih.gov/pubmed/26807165
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