Epigenetic regulation in chondrocyte phenotype maintenance for cell-based cartilage repair

Loss of hyaline chondrocyte phenotype during the monolayer culture in vitro is a major obstacle for cell-based articular cartilage repair. Increasing evidence implicates an important role of the epigenetic regulation in maintaining the chondrocyte phenotype. DNA methylation, histone modifications an...

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Vydáno v:Am J Transl Res
Hlavní autoři: Duan, Li, Liang, Yujie, Ma, Bin, Zhu, Weimin, Wang, Daping
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2015
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697695/
https://ncbi.nlm.nih.gov/pubmed/26807163
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