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Sickle cell trait diagnosis: clinical and social implications

The sickle hemoglobin (HbS) point mutation has independently undergone evolutionary selection at least five times in the world because of its overwhelming malarial protective effects in the heterozygous state. In 1949, homozygous Hb S or sickle cell disease (SCD) became the first inherited condition...

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Detalhes bibliográficos
Publicado no:Hematology Am Soc Hematol Educ Program
Main Authors: Naik, Rakhi P., Haywood, Carlton
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697437/
https://ncbi.nlm.nih.gov/pubmed/26637716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2015.1.160
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