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Sickle cell trait diagnosis: clinical and social implications

The sickle hemoglobin (HbS) point mutation has independently undergone evolutionary selection at least five times in the world because of its overwhelming malarial protective effects in the heterozygous state. In 1949, homozygous Hb S or sickle cell disease (SCD) became the first inherited condition...

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Dettagli Bibliografici
Pubblicato in:Hematology Am Soc Hematol Educ Program
Autori principali: Naik, Rakhi P., Haywood, Carlton
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697437/
https://ncbi.nlm.nih.gov/pubmed/26637716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2015.1.160
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