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Sickle cell trait diagnosis: clinical and social implications
The sickle hemoglobin (HbS) point mutation has independently undergone evolutionary selection at least five times in the world because of its overwhelming malarial protective effects in the heterozygous state. In 1949, homozygous Hb S or sickle cell disease (SCD) became the first inherited condition...
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| Publicado en: | Hematology Am Soc Hematol Educ Program |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697437/ https://ncbi.nlm.nih.gov/pubmed/26637716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2015.1.160 |
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