Local sources of retinoic acid coincide with retinoid-mediated transgene activity during embryonic development.

We have assessed whether retinoic acid (RA) comes from local sources or is available widely to activate gene expression in embryos. We used an RA-responsive indicator cell line, L-C2A5, to localize RA sources. In these cells, an RA-sensitive promoter/lacZ reporter construct used previously by us to...

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Bibliografske podrobnosti
Main Authors: Colbert, M C, Linney, E, LaMantia, A S
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC46974/
https://ncbi.nlm.nih.gov/pubmed/8341670
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