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Chemical disruption of Wnt-dependent cell fate decision-making mechanisms in cancer and regenerative medicine

Cell-to-cell signaling molecules such as the Wnt proteins that directly influence the expression of cell-type specific transcriptional programs are essential for tissue generation in metazoans. The mechanisms supporting cellular responses to these molecules represent potential points of intervention...

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Detalhes bibliográficos
Publicado no:Curr Med Chem
Main Authors: Lum, Lawrence, Chen, Chuo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697282/
https://ncbi.nlm.nih.gov/pubmed/26310918
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