Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE

TGFβ-induced expression of the NADPH oxidase Nox4 is essential for fibroblast-myofibroblast transition. Rho has been implicated in Nox4 regulation, but the underlying mechanisms are largely unknown. Myocardin-related transcription factor (MRTF), a Rho/actin polymerization-controlled coactivator of s...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Rozycki, Matthew, Bialik, Janne Folke, Speight, Pam, Dan, Qinghong, Knudsen, Teresa E. T., Szeto, Stephen G., Yuen, Darren A., Szászi, Katalin, Pedersen, Stine F., Kapus, András
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697158/
https://ncbi.nlm.nih.gov/pubmed/26555261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.674606
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