Targeting Th17 Cells with Small Molecules and Small Interference RNA

T helper 17 (Th17) cells play a central role in inflammatory and autoimmune diseases via the production of proinflammatory cytokines interleukin- (IL-) 17, IL-17F, and IL-22. Anti-IL-17 monoclonal antibodies show potent efficacy in psoriasis but poor effect in rheumatoid arthritis (RA) and Crohn...

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Detalles Bibliográficos
Publicado en:Mediators Inflamm
Main Authors: Lin, Hui, Song, Pingfang, Zhao, Yi, Xue, Li-Jia, Liu, Yi, Chu, Cong-Qiu
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2015
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697089/
https://ncbi.nlm.nih.gov/pubmed/26792955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/290657
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