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Improving the Immunogenicity of the Mycobacterium bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System

Current strategies to improve the current BCG vaccine attempt to over-express genes encoding specific M. tuberculosis (Mtb) antigens and/or regulators of antigen presentation function, which indeed have the potential to reshape BCG in many ways. However, these approaches often face serious difficult...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Liao, Ting-Yu Angela, Lau, Alice, Joseph, Sunil, Hytönen, Vesa, Hmama, Zakaria
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696857/
https://ncbi.nlm.nih.gov/pubmed/26716832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145833
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