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Identifying and Reducing Systematic Errors in Chromosome Conformation Capture Data

Chromosome conformation capture (3C)-based techniques have recently been used to uncover the mystic genomic architecture in the nucleus. These techniques yield indirect data on the distances between genomic loci in the form of contact frequencies that must be normalized to remove various errors. Thi...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Hahn, Seungsoo, Kim, Dongsup
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696798/
https://ncbi.nlm.nih.gov/pubmed/26717152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146007
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