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Modeling error in experimental assays using the bootstrap principle: Understanding discrepancies between assays using different dispensing technologies

All experimental assay data contains error, but the magnitude, type, and primary origin of this error is often not obvious. Here, we describe a simple set of assay modeling techniques based on the bootstrap principle that allow sources of error and bias to be simulated and propagated into assay resu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Comput Aided Mol Des
Prif Awduron: Hanson, Sonya M., Ekins, Sean, Chodera, John D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696763/
https://ncbi.nlm.nih.gov/pubmed/26678597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-015-9888-6
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