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Modeling error in experimental assays using the bootstrap principle: Understanding discrepancies between assays using different dispensing technologies

All experimental assay data contains error, but the magnitude, type, and primary origin of this error is often not obvious. Here, we describe a simple set of assay modeling techniques based on the bootstrap principle that allow sources of error and bias to be simulated and propagated into assay resu...

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Detalhes bibliográficos
Publicado no:J Comput Aided Mol Des
Main Authors: Hanson, Sonya M., Ekins, Sean, Chodera, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696763/
https://ncbi.nlm.nih.gov/pubmed/26678597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-015-9888-6
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