Genetic Evidence for the Role of the Vacuole in Supplying Secretory Organelles with Ca(2+) in Hansenula polymorpha

Processes taking place in the secretory organelles require Ca(2+) and Mn(2+), which in yeast are supplied by the Pmr1 ion pump. Here we observed that in the yeast Hansenula polymorpha Ca(2+) deficiency in the secretory pathway caused by Pmr1 inactivation is exacerbated by (i) the ret1-27 mutation af...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fokina, Anastasia V., Chechenova, Maria B., Karginov, Azamat V., Ter-Avanesyan, Michael D., Agaphonov, Michael O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696657/
https://ncbi.nlm.nih.gov/pubmed/26717478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145915
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