Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN

Necrotizing and crescentic rapidly progressive GN (RPGN) is a life-threatening syndrome characterized by a rapid loss of renal function. Evidence suggests that podocyte expression of the transcription factor peroxisome proliferator-activated receptor γ (PPARγ) may prevent podocyte injury, but the fu...

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Foilsithe in:J Am Soc Nephrol
Main Authors: Henique, Carole, Bollee, Guillaume, Lenoir, Olivia, Dhaun, Neeraj, Camus, Marine, Chipont, Anna, Flosseau, Kathleen, Mandet, Chantal, Yamamoto, Masayuki, Karras, Alexandre, Thervet, Eric, Bruneval, Patrick, Nochy, Dominique, Mesnard, Laurent, Tharaux, Pierre-Louis
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2016
Ábhair:
Basic Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696572/
https://ncbi.nlm.nih.gov/pubmed/25999406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014111080
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