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Modified mRNA as an alternative to plasmid DNA (pDNA) for transcript replacement and vaccination therapy
Introduction: Current gene therapy involves replacement of defective gene by delivery of healthy genetic material to precede normal function. Virus-mediated gene delivery is the most successful and efficient method for gene therapy, but it has been challenged due to serious safety concerns. Converse...
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| Pubblicato in: | Expert Opin Biol Ther |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Informa Healthcare
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4696419/ https://ncbi.nlm.nih.gov/pubmed/26125492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1057563 |
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